Method of production of drugs: Mr injection 0,02% 1 ml in amp. Side effects and complications in the use of drugs: the mother - grapheme embolism pulmonary embolism amniotic fluid, cardiac arrest, abnormal contraction of the uterus (increased frequency, duration or tone), uterine rupture, rapid dilatation of the cervix, placenta abruption, nausea, vomiting, diarrhea, raising t ° (fever), back pain, bronchospasm, asthma, rash, hypersensitivity reactions, grapheme vazovazalni symptoms (hot flashes, tremor, headache, dizziness), tissue irritation at the injection site - grapheme increasing the number of leukocytes in the blood in fruit - distress-with-m and HR violations, reducing the assessment by Apgar score, mertvonarodzhuvanist, neonatal death. Indications for use drugs: Abortion in second trimester in these cases - the Unfinished spontaneous abortion, fetal death In vitro fertilization uterus, grave violations of growth retardation, inborn developmental disorders that are incompatible with life, which are defined by current diagnostic procedures, artificial abortion when it is impossible because of the risk of complications in the mother during his holding (to the grapheme trimester); local treatment of severe bleeding at pislyapolohoviyi placental stage. Contraindications to the use of drugs: hypersensitivity to the drug to other drugs in history uterotonichnyh; anatomically and clinically narrowed pelvis or fetal malpresentation; existing asthma or a history, Mr and Mts obstructive lung disease, active phase of ulcerative colitis, Crohn's disease, thyrotoxicosis, G infection, inflammation of the urogenital system or abdominal cavity, the disturbance of the amniotic membrane, falciform cell anemia, glaucoma, hypertension (160/100 mmHg. Side effects and complications in grapheme use of drugs: diarrhea, nausea, pain or cramping in the stomach, vomiting, severe and prolonged pain in the stomach, bowel paralysis, peripheral vascular spasm, bradycardia, Every Morning AV-block I degree, crushing sensation or pain section of the sternum, bronchospasm, prolonged cough, grapheme paresthesia, headache, drowsiness, feeling of tension; violation of urination, hematuria, urinary retention, pain in the uterus during an abortion, hypertension, cancer, anaphylactic shock, burning in the eyes, pain in the back leg and shoulder joints, increasing the number of leukocytes, "ant"; chills or sweating, transient fever, redness, increased mammary gland caused by an influx of blood to them, burning sensation in the nipple, inflammation and grapheme at the injection site; thirst. Method of production of drugs: Mr injection, 5 mg / 1 ml to 1 ml in amp. Pharmacotherapeutic group: G02AD01 - tools to improve the tone and the contractile activity of myometrium. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, headache, dizziness, tinnitus, rare - hallucinations, vascular spasm, disturbance of extremities, increased blood pressure, tachycardia (sometimes - bradycardia), shortness of breath. Indications for use drugs: induction of labor in women with mature or nearly full-term pregnancy; gel is used for softening (ripening) of cervix, if necessary, induction of labor activity by Minnesota Multiphasic Personality Inventory or obstetrical indications. Prostaglandins. The main pharmaco-therapeutic effects: uterotonichna action; prostaglandin F2-alpha (reduced forms of prostaglandin E2) dynoprost promotes maturing cervix, and on the other hand - maternity stimulates activity.
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