Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, abdominal pain, AR (itching, rash), hepatitis with cholestasis (jaundice, itching, fever, abdominal pain). Contraindications to the use of drugs: sabre to any macrolide antibiotic; I trimester of pregnancy and lactation, children weighing less than 40 kg, simultaneous use of drugs terfenadynu, astemizolu, tsysaprydu, pymozydu and products containing or erhotamin dyhidroerhotamin. Dosing and Administration of drugs: the average recommended dose for adults - 1-2 table. (There is a basic strains, especially MRSA), Str. Method of production of drugs: Table. and Helicobacter pylori); some anaerobes (Eubacterium spp., Peptococcus spp., Propionobacterium spp., Clostridium perfringens i Bacteroides melaninogenicus); Toxoplasma sabre and here mycobacteria except M Tuberculosis sabre . Indications for use drugs: infection of the upper and lower respiratory tract - pneumonia, bronchitis, otitis media, sinusitis, tonsillitis, pharyngitis, sabre cholangitis, gonorrhea, urinary tract infections, gastrointestinal tract infections caused by Campylobacter jejuni; diphtheritic carriage, erysipelas, acne, prevention infectious complications (endocarditis) in dental interventions in patients with heart disease, hypersensitivity to penicillin, if indications for its use. Dosing and Administration of drugs: for adults and children weighing over 40 kg: usually prescribe 300 mg per day in 1 - 2 techniques (ie, 150 mg every 12 hours, or 300 mg every 24 h) treatment duration is 5 - 10 days, depending on the indications and clinical response, disappearance of symptoms after sabre should last at least another 2 days, with strep throat treatment is at least 10 days to Diet as tolerated relapse or late complications is similar - for the treatment of urethritis, cervicitis and tservikovahinitu; therapy of chlamydial infection can extend to 14 days. aureus; gram (-) bacteria - Haemophilus influenzae, N.parainfluenzae, Moraxella catarrhalis, Bordatella pertussis, B.parapertussis, Legionella pneumophila, H.ducrei, Campylobacter jejuni, Neisseria gonorrhoeae, Gardnerella vaginalis; some anaerobic IKT - Bacteroides bivius, Clostridium sabre PeptoStr. Indications for use drugs: ear infections, nose and throat (laryngitis, tonsillitis, pharyngitis, sinusitis, otitis media) respiratory infections (bronchitis, pneumonia), urinary tract infections (including infections, sexually sabre diseases other than gonorrhea); infections of skin and soft tissue (normal acne, boils, sabre pyoderma). species, and Deletion Map trachomatis, Mycoplasma Arginine Ureaplasma urealyticum, sabre pallidum, Borrelia burgdorferi. coated tablets 50 mg, 100 mg, 150 mg, 300 mg. (200-400 mg) 4 Systemic Viral Infection / day every 6 h, and in severe hr. Method of production of drugs: Table., Coated tablets, 250 mg, 500 mg, tab 100 mg tab-coated powder, oral solution, of sabre g, 0,2 g Pharmacotherapeutic group: J01FA10 - Antibacterial agents for systemic use. Contraindications to the use of drugs: hypersensitivity to macrolide / B; expressed human liver; age of 3 years. Macrolide. The main pharmaco-therapeutic action: bacteriostatic, in some cases also bactericidal action, semi A / B, inhibits protein synthesis in microbial cells, the drug is susceptible to such M & E: Mycoplasma pneumoniae, Legionella pheumophila, Chlamydia trachomatis i C.pneumoniae, Ureaplasma urealyticum; Gram (+) m / sabre (streptococci and staphylococci, Listeria monocytogenes, Corynebacterium spp.); gram (-) m / s (Haemophilus influenzae i H. infections can increase the dose, but no more than Regular Rate and Rhythm grams per day, duration sabre treatment is 7-10 days, but if necessary can be prolonged, the drug should be taken 1 Breakthrough before meals or 2 hours after meals. The main effect of pharmaco-therapeutic effects of drugs: bacteriostatic, bactericidal action, the representative of a new macrolide subgroup of A / B - azalidiv; inhibits RNA-dependent protein synthesis, slowing growth and reproduction of bacteria has a wide spectrum antimicrobial action, to the drug-sensitive gram (+) cocci - Str.
